Synthetic Chemist

Job Summary

We are seeking a highly motivated and skilled Synthetic Chemist to join our Synthesis Department. The incumbent will be responsible for the synthesis, purification, characterization, and scale-up of novel compounds, intermediates, and APIs. The role requires strong knowledge of organic chemistry, name reactions, analytical data interpretation, and laboratory documentation practices.

Key Responsibilities

• Execute multi-step organic synthesis of intermediates, impurities, novel compounds, and APIs.
• Perform reaction screening, process optimization, and scale-up activities.
• Carry out compound purification using column chromatography, recrystallization, and other purification techniques.
• Design and execute synthetic routes based on literature and project requirements.
• Conduct literature searches to support route scouting, process development, and troubleshooting.
• Interpret analytical data including LC-MS, NMR, IR, and other spectroscopic techniques.
• Ensure accurate and timely documentation of experimental procedures, observations, and results.
• Prepare technical reports, batch records, SOPs, and project documentation.
• Analyze critical reaction parameters and identify opportunities for process improvement.
• Adhere to laboratory safety, quality, and compliance requirements.
• Collaborate with cross-functional teams for project execution and successful delivery.

Educational Qualification

• Ph.D. in Chemistry OR
• M.Sc. in Chemistry / Applied Chemistry OR
• M.Pharm.

Mandatory Skills

• Organic Synthesis and General Chemistry
• Column Chromatography
• Name Reactions and Reaction Mechanisms
• Scale-up Activities
• Scientific Documentation
• Computer Proficiency (MS Office, Electronic Documentation Systems)
• Experimental Design and Troubleshooting

Preferred / Desirable Skills

• Development of Unknown Compounds
• API Synthesis and Process Development
• Literature Search and Patent Review
• Process Optimization
• Column Chromatography Techniques
• Technical Report Writing
• Impurity Synthesis and Characterization

Technical Competencies

• LC-MS (Liquid Chromatography-Mass Spectrometry)
• NMR Spectral Interpretation
• IR Spectroscopy Interpretation
• Analytical Data Evaluation
• Critical Condition/Reaction Parameter Analysis
• Purification and Characterization Techniques
• Laboratory Documentation and Compliance

Experience

• Executive: 13 years
• Sr. Executive: 3–6 years
• Scientist: 6+ years

Key Attributes

• Strong analytical and problem-solving skills
• Attention to detail and data integrity
• Ability to work independently and within project timelines
• Good communication and teamwork skills
• Strong scientific aptitude and innovation mindset