Senior Manager, Clinical Site Payments, Portfolio Management

This position is listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Senior Manager, Clinical Site Payments, Portfolio Management based in United States.

This is a strategic finance and operations role overseeing the financial management of investigator grant payments across a global clinical trial portfolio. You will sit at the intersection of Clinical Operations, Finance, Treasury, Sourcing, and regional payment teams. The role owns portfolio-level reconciliation, accruals, forecasting, Budget vs. Actuals analysis, and financial close activities. You will build financial models and scenarios that help leaders understand cash flow, liabilities, operational changes, and portfolio risk. The position also leads payment analytics, KPI reporting, data alignment, and dashboard development to improve financial visibility. Strong governance and audit readiness are central, with responsibility for SOX controls, documentation, reconciliations, and external audit support. This opportunity is ideal for a highly analytical finance professional who thrives in a global, fast-paced pharmaceutical or biotech environment.

Accountabilities:: Portfolio financial oversight: Lead monthly reconciliation of global investigator grant expenses, aligning site payments, vendor disbursements, financial ledgers, accruals, commitments, and outstanding liabilities.

Payment and PO management: Oversee Purchase Requisitions and Purchase Orders for clinical site payments and vendors, ensuring they accurately reflect study budgets, amendments, forecasted spend, utilization, and closeout requirements.

Vendor invoice management: Review and validate vendor invoices and drawdowns in collaboration with Sourcing and Finance teams, ensuring appropriate funding levels and supporting documentation.

Accruals and financial close: Own monthly PO accrual analysis and reporting, ensuring accurate investigator grant accruals, compliance with financial close timelines, and alignment with SOX requirements.

Budget vs. Actuals analysis: Perform study- and portfolio-level BvA analysis to identify variances, trends, financial risks, and opportunities, partnering with Finance and Treasury to support accurate financial close.

Closeout and liability forecasting: Develop a strong understanding of site-level financial closeout processes and forecast outstanding expenses incurred but not yet invoiced, ensuring adequate accrual coverage and accurate liability reporting.

Financial modeling and forecasting: Build and maintain models for accrual forecasting, cash-flow projections, scenario analysis, internalization strategies, enrollment changes, study delays, vendor mix, and foreign-exchange impacts.

Portfolio analytics: Own the Clinical Site Payments KPI framework, reporting cadence, and analytics dashboards, including metrics covering payment cycle times, accrual accuracy, forecast deviations, vendor performance, and financial trends.

Data governance: Partner with Budget Planning & Strategy, Clinical Site Contracts, and Clinical Site Data teams to align payment data with approved budgets, negotiated contracts, CPT codes, categories, subcategories, and established data structures.

Cross-functional partnership: Serve as a key liaison between Clinical Site Payments, Finance, Treasury, Clinical Operations, and other stakeholders, supporting strategic initiatives such as payment internalization and process optimization.

Governance and controls: Ensure adherence to SOX and internal financial control frameworks, maintain audit-ready documentation, identify control gaps, and drive improvements in financial governance.

Audit support: Lead preparation for quarterly external audits by coordinating documentation and validating audit samples with regional payment teams, Finance, and Controller stakeholders.

Requirements:

Education and experience: Bachelor’s degree from an accredited institution with at least 7+ years of experience in finance, biotechnology, pharmaceuticals, or a related field within the biotech/pharmaceutical industry.

Clinical finance expertise: Previous experience in clinical trial finance, clinical site budgeting, clinical payments, vendor sourcing, clinical operations, finance, and/or accounting.

Industry background: Strong understanding of clinical development and drug development environments within the pharmaceutical or biotechnology sector.

Financial modeling: Proven ability to build and maintain financial models, including cash-flow forecasts, accrual projections, scenario analysis, and portfolio-level financial forecasts.

Financial controls: Strong knowledge of SOX compliance, internal financial controls, financial close processes, audit readiness, reconciliations, and documentation standards.

Systems expertise: Advanced proficiency with Microsoft Office, particularly Excel, as well as experience with financial systems such as SAP, Oracle, Ariba, and Agiloft and clinical payment vendor platforms.

Data and analytics: Ability to manipulate, analyze, interpret, and communicate complex financial and operational data and develop meaningful reporting and dashboards.

Project and process management: Experience in clinical business operations, business process management, and/or project management, with the ability to manage multiple priorities and compressed timelines.

Analytical mindset: Exceptional attention to detail, accuracy, critical thinking, problem-solving ability, and a proactive approach to identifying and resolving financial issues.

Communication and collaboration: Strong interpersonal, leadership, negotiation, and communication skills, with the ability to work effectively across global, cross-functional teams.

Work style: Self-directed and adaptable, with the ability to prioritize competing demands, work independently, exercise sound judgment, and deliver consistently in a fast-paced environment.

Language: Fluency in written and verbal English.

Travel: Willingness to travel as needed.

Benefits:

Annual base salary: $136,400–$181,400, with actual compensation determined by experience, qualifications, education, certifications, and location.

Eligibility for an annual bonus plan for non-commercial roles.

Opportunity for equity awards and participation in an Employee Stock Purchase Plan.

Comprehensive medical, dental, and vision coverage.

401(k) retirement benefits.

FSA/HSA options.

Life insurance coverage.

Paid time off .

Wellness benefits .

Remote work environment in the United States.

Opportunity to work on global clinical payment operations and high-impact financial initiatives within a growing pharmaceutical organization.

How Jobgether works: We use an AI-powered matching process to ensure your application is reviewed quickly, objectively, and fairly against the role's core requirements. Our system identifies the top-fitting candidates, and this shortlist is then shared directly with the hiring company. The final decision and next steps (interviews, assessments) are managed by their internal team. We appreciate your interest and wish you the best!  Why Apply Through Jobgether?    Data Privacy Notice: By submitting your application, you acknowledge that Jobgether will process your personal data to evaluate your candidacy and share relevant information with the hiring employer. This processing is based on legitimate interest and pre-contractual measures under applicable data protection laws (including GDPR). You may exercise your rights (access, rectification, erasure, objection) at any time.     #LI-CL1