Scientist II, Protein Biology

Job Description :

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Cold Room/Freezers -22degreesF/-6degrees C, Laboratory Setting, Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.)

As part of the Thermo Fisher Scientific team, you'll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world's toughest challenges, like protecting the environment, making sure our food is safe or helping find cures for cancer.

DESCRIPTION:
Join our collaborative Antibody Development team at Thermo Fisher Scientific, where you'll contribute to advancing protein and antibody engineering technologies. As a Scientist II in Protein Biology, you'll be part of our team focused on designing, developing, and validating high-quality antibodies using advanced tools and methodologies. You'll contribute to research that enables our customers to make the world healthier, cleaner, and safer.

About Team: Protein Biology

The Protein Biology team is involved in large-scale functional validation of antibodies, with a deep focus on reagent quality and specificity. The core activities of the team include data mining and processing, Western blotting with state-of-art tools, high efficiency and high-resolution immuno-fluorescence imaging, immunohistochemistry, ChIP (Chromatin Immunoprecipitation), and gene-silencing to provide advance application tags to our antibody portfolio. The program's goal is high-quality product validation and product information creation to promote research use.

Role & Responsibilities

Purpose: - Contribute to the antibody validation workflow. Understand target biology validation and validate antibodies for reproducibility using innovative methods and crafting data sets to enable market differentiation. The role of the successful candidate would entail demonstrating scientific proficiency in experimental planning and execution. Prior experience in working in a research team, with a proven track record of setting goals, handling work-related customer concerns, and ensuring timely delivery in alignment with the program goals. Proficiency in verbal and written communication of results in the workplace is helpful.

Responsibilities:

• Acquire and utilize knowledge on key aspects of protein biology, to deliver results on antibody validation and characterization.
• Regular mining of literature and keeping oneself up to date with developments in field of antibody validation.
• Perform in a fast- paced environment towards antibody validation, with attention to detail and adherence to schedules.
• Informal leadership of team of scientists in matrix style operation, provide technical and operational supervision. Mentoring and training junior scientists in research, design and experimental execution, interpreting data and data presentation to collaborators and partners.
• Drive conceptualization within teams to enable development of successful protocols to address complex biological targets
• Partner with supporting functions such as product management, program management, and business development to meet program goals.

Candidate Requirement:

Education & Experience levels:

• Applicants should have Masters degree with upto 5 years of experience or a PhD in molecular biology, cell biology, genetics, immunology, biotechnology, computational biology or biochemistry with 2 to 3 years experience.

Skills:

• Familiar with experimental workflow in cell and molecular biology, with extensive experience in the design and development of protein-assays, protein-protein interaction (using co-immunoprecipitation), or development of immunoassays.
• Proven and extensive experience in Flow cytometry, and ELISA. Good working knowledge of western blotting and immunofluorescence is desirable.
• Communication of research data and providing expert-level technical troubleshooting to resolve scientific problems and develop new protocols/methods.

• Good understanding of statistical and computational biology tools.
• Working knowledge of databases and programming languages is desirable.

• Experience in antibody development platforms is desirable.