Scientist Cancer Immunology & Single-Cell Genomics

About AnuBio:

AnuBio is building a multicellular foundation model of the human immune system to transform drug discovery. Our platform, TRAILBLAZER™, creates predictive digital twins of patient immunity—enabling discovery of new therapies without predefined molecular targets.

We operate at the intersection of single-cell biology and AI, with active programs across immuno-oncology, autoimmune disease, and neuroinflammation. Our team includes scientists from leading global institutions, and we are rapidly scaling our data generation engine.

The Role: We are hiring a Scientist with expertise in cancer immunology and single-cell genomics to build experimental programs studying immune responses to therapeutic perturbations. You will design and execute immune-cell perturbation studies, develop and scale our single-cell genomics capabilities, and generate high-quality datasets for predictive modelling and therapeutic discovery. This is a high-autonomy role for someone who combines a strong understanding of immune biology with hands-on experimental experience.

What You'll Do:

• Design and execute immune perturbation experiments using primary human immune cells
• Study immune activation, checkpoint biology and therapeutic response/resistance
• Establish, optimize and scale single-cell RNA-seq workflows
• Own experiments end-to-end, from experimental design & cell perturbation to library prep, QC and sequencing
• Scale workflows to hundreds of samples/conditions and 1M cells
• Troubleshoot and improve assay quality, reproducibility, cost and throughput
• Interpret single-cell data in the context of cancer immunology and therapeutic mechanisms
• Collaborate with ML and computational biology teams on experimental design and predictive modelling
• Build and mentor a growing wet-lab team

Required Qualifications:

• PhD in immunology, cancer biology, molecular biology, genomics or a related field
• Strong experimental background in immunology and/or cancer immunology
• Experience with cell prep (PBMCs, nuclei, fixation methods) 
• Hands-on experience with single-cell RNA-seq (Parse Evercode, SPLiT-seq, sci-RNA-seq, etc.) 
• Experience with NGS library preparation and QC
• Strong understanding of experimental controls, biological variability and assay design
• Ability to take ownership of experimental programs with minimal supervision

Preferred:

• Direct Experience in tumor immunology, immune checkpoint biology or ICI cancer immunotherapy
• Experience studying responses to cytokines, antibodies or other immune perturbations
• Experience developing genomics assays (NGS, library prep, nucleic acids enzymatic assays)
• Experience with flow cytometry and immune-cell phenotyping
• Familiarity with single-cell analysis tools such as Scanpy or Seurat
• Experience with automation or high-throughput experimental workflows

Who Thrives Here:

• Connects biology, experiments and data to answer meaningful scientific questions
• Takes ownership of complex experiments and troubleshoots independently
• Curious about immune responses to perturbations and therapies and their underlying mechanisms

What We Offer

• High-impact work at the frontier of AI, immunology and therapeutic discovery
• Close collaboration with scientists, founders and ML team 
• Competitive salary 

Apply: Send your CV and a short note to [HIDDEN TEXT] answering:

Tell us about a challenging immune or single-cell experiment you designed or rescued. What went wrong, what did you change, and what did you learn