Research Scientist Drug Discovery

Job Title

Research Scientist

Function / Department

Drug Discovery

Employment Type

Full-Time, Permanent

Location

On-site

POSITION OVERVIEW

The candidate will identify and evaluate new therapeutic indications for approved drugs using pharmacological, preclinical, and clinical evidence. The role involves literature mining, target identification, mechanism-of-action studies, safety assessment, and preparation of scientific reports for drug repurposing projects.

KEY RESPONSIBILITIES

• Conduct comprehensive literature searches for drug repurposing opportunities.
• Analyze pharmacodynamics, pharmacokinetics, and toxicity data of approved drugs.
• Evaluate the applicability of drugs in new indications based on molecular mechanisms.
• Review preclinical (in vitro and in vivo) and clinical evidence for repurposing candidates.
• Assess translational potential from animal studies to human applications.
• Prepare scientific reports, review articles, and regulatory summaries.
• Perform target-pathway analyses involving inflammation, fibrosis, oxidative stress, and signaling pathways.
• Evaluate safety profiles, contraindications, and limitations of repurposed drugs.
• Collaborate with medicinal chemists, clinicians, and regulatory teams.

REQUIREMENTS

Education & Experience

• M.Pharm (Pharmacology) or Pharm.D
• Minimum 2 years of experience in pharmacology, preclinical research, medical writing, or clinical research
• Experience in literature review, drug repurposing, and mechanism-based research is preferred

Technical Skills

• Strong knowledge of pharmacology and pathophysiology
• Drug repurposing strategies and translational medicine concepts
• Literature databases: PubMed, Scopus, Embase
• Understanding of FDA, EMA, and CDSCO regulatory pathways
• Knowledge of pharmacokinetics, toxicology, and pharmacodynamics
• Scientific writing and data interpretation
• Statistical analysis and data presentation
• Experience with animal-to-human dose conversion and preclinical evaluation

Core Competencies

• Excellent problem-solving skills, with the ability to analyze complex, multi-modal datasets and derive actionable insights.
• Strong written and verbal communication skills, able to convey technical findings to a multidisciplinary, non-technical audience.
• Proven ability to collaborate effectively within cross-functional, multidisciplinary teams.