QC Chemist - Gas Chromatography (GC)

Location: Vadodara, Surendranagar

Job Purpose

To perform routine and specialized analysis of raw materials, intermediates, finished products, solvents, and other QC samples using GC, in accordance with approved specifications, analytical methods, SOPs, and GMP requirements.

Key Responsibilities

• Perform routine analysis of QC samples using GC.
• Operate, calibrate, and maintain GC instruments as per approved SOPs.
• Perform standard and sample preparation and chromatographic analysis.
• Perform system suitability tests and evaluate chromatographic results.
• Review chromatograms, peak identification, integration, calculations, and analytical data.
• Perform GC analysis for residual solvents, assay, purity, related substances, and other applicable parameters.
• Troubleshoot GC-related issues, including baseline problems, peak shape, retention time variation, sensitivity, and gas supply-related issues.
• Maintain analytical worksheets, instrument logbooks, raw data, and other QC documentation.
• Ensure compliance with GMP, GLP, data integrity, and laboratory safety requirements.
• Support method validation, method verification, method transfer, and analytical method development activities.
• Support OOS/OOT investigations and provide appropriate analytical inputs.
• Participate in instrument calibration, qualification, and preventive maintenance activities.
• Ensure proper handling and storage of samples, standards, solvents, and gases.
• Maintain good housekeeping and safety practices in the QC laboratory.

Required Qualification

• B.Sc./M.Sc. in Chemistry, Pharmaceutical Chemistry, Analytical Chemistry, or a related field.
• Diploma/Bachelors degree in Pharmacy may also be considered based on experience.

Experience

• 1+ years of relevant experience in a pharmaceutical/API QC laboratory.
• Hands-on experience in GC analysis is required.
• Experience with Shimadzu, Agilent, PerkinElmer, Thermo Fisher, or equivalent GC systems will be preferred.

Required Skills

• Good knowledge of GC operation and troubleshooting.
• Knowledge of residual solvent analysis and chromatographic techniques.
• Good understanding of GMP, GLP, SOPs, and data integrity.
• Strong analytical and documentation skills.
• Ability to investigate analytical problems and work within defined timelines.
• Good communication and teamwork skills.