Openings For Formulation Development- Oral Solids

Role & responsibilities

Executive / Senior Executive / Assistant Manager / Junior Manager

Company: MSN Laboratories Pvt. Ltd.
Department: Formulation Research & Development (FR&D)
Function: Oral Solid Dosage (OSD)
Experience: 28 Years
Qualification: M.Pharm / B.Pharm in Pharmaceutics, Industrial Pharmacy, Pharmaceutical Technology, or related specialization

Position Summary

The position is responsible for execution and/or leadership of Oral Solid Dosage (OSD) formulation development activities, including pre-formulation, prototype development, formulation optimization, process development, scale-up, exhibit/registration batches, stability studies, troubleshooting, and technology transfer.

The candidate will work closely with Analytical R&D, IPQA, Production, QC, Regulatory Affairs, Packaging, and other cross-functional teams to ensure timely development of robust, scalable, and regulatory-compliant formulations.

Key Responsibilities

1. Pre-Formulation & Product Development

• Conduct pre-formulation studies for APIs and excipients, including:
• Solubility and pKa
• Particle size and morphology
• Bulk/tapped density
• Flow properties
• Compressibility
• Polymorphism/solid-state characteristics
• Drug–excipient compatibility
• Evaluate API characteristics and identify formulation challenges.
• Select appropriate excipients based on functionality, compatibility, product performance, and regulatory requirements.
• Develop formulation prototypes based on the QTPP and target product profile.
• Develop and optimize immediate-release and, where applicable, modified-release OSD formulations.

2. Formulation Development

• Plan and execute formulation trials for tablets and capsules.
• Develop formulations using appropriate manufacturing approaches such as:
• Direct compression
• Dry granulation
• Wet granulation
• Fluid-bed granulation
• Pellet/multiparticulate technology, where applicable
• Optimize formulation variables to achieve desired CQAs such as:
• Assay
• Content uniformity
• Dissolution
• Related substances
• Disintegration
• Hardness
• Friability
• Weight variation
• Conduct comparative dissolution studies and support formulation selection.
• Identify and resolve formulation-related problems during development.