MSAT Upstream

Biocon is a global biopharmaceutical company transforming patients lives in over 120 countries. Guided by our vision to deliver affordable, innovative healthcare solutions, we develop treatments for diabetes, cancer, and autoimmune diseases. At Biocon, we value integrity, innovation, and inclusion, fostering a culture that empowers our people to make a meaningful impact on global health.

Qualifications:

• Education: Bachelor's, Master's, Biotechnology, Biochemical Engineering, or related field.
• Experience: Minimum of 18 months - 3 years of experience in cell culture, bioprocessing, or biomanufacturing, with a focus on upstream processes (e.g., mammalian cell culture, bioreactor operation, media optimization).

Key Responsibilities:

• MSAT Lab Management: Manage MSAT lab where the responsibilities include SOP revision, Management of deviations in Lab, Batch trials, Inventory management, etc.
• Scale-Up and Technology Transfer: Support the scale-up and technology transfer of cell culture processes to GMP (Good Manufacturing Practice) environments.
• Troubleshooting and Problem-Solving: Identify, investigate, and resolve technical issues related to cell culture performance, yield, and quality.
• Process Monitoring: Monitor ongoing cell culture processes, including cell density, viability, and product yield. Analyse data to ensure optimal performance and compliance with regulatory requirements.
• Cross-Functional Collaboration: Work with process development, quality assurance, and production teams to ensure seamless process transfers and support manufacturing campaigns.
• Documentation and Compliance: Maintain accurate records of experiments, process changes, and deviations. Ensure all activities are in compliance with SOPs (Standard Operating Procedures) and regulatory guidelines.
• Process Optimization: Design and execute experiments to optimize cell culture processes.
• Continuous Improvement: Participate in the implementation of process improvements to enhance productivity, efficiency, and product quality.

Technical Skills:

• Proficient in cell culture techniques (e.g., batch, fed-batch, continuous processes).
• Experience with mammalian cell lines (e.g., CHO cells).
• Familiarity with bioreactor systems (e.g., single-use, stirred tank).
• Hands-on experience with automated bioreactor systems and process control software.
• Strong data analysis skills and experience with process monitoring tools and DOE approach.
• Experience in technology transfer and scale-up activities.
• Familiarity with GMP and regulatory requirements in biomanufacturing.
• Basic understanding about statistical tools like JMP, SIMCA is a plus.

Soft Skills:

• Strong problem-solving and critical thinking abilities.
• Ability to work independently and within a team.
• Excellent written and verbal communication skills.