Individual contributor

Role: Individual contributor role

Location: Manyata Tech Park, Bangalore.

About Alexion

At Alexion, our mission is to transform the lives of people affected by rare diseases through the development and delivery of innovative medicines as well as supportive technologies and healthcare services.

Introduction to role:

Do you thrive at the intersection of statistics, real-world evidence, and regulatory science Step into a role where your expertise in disease registries and longitudinal observational cohorts directly advances therapies for patients. You will lead the development of regulatory-grade evidence from real-world data, guiding submissions that can speed approvals, support label expansions, and fulfill post-market commitments.

Can you envision turning registry data into decisive insights that withstand health authority scrutiny Joining our growing epidemiology and real-world evidence capability, you will apply statistical methodologies tailored for registries, align to AstraZeneca standards, and contribute to a portfolio that demands rigor, creativity, and impact.

Accountabilities:

Registry Evidence Strategy: Oversee the statistical vision and analytical strategies for registry-based evidence, crafting regulatory submissions and decisions across rare disease programs.

Regulatory-Grade Analyses: Oversee the design, implementation, and validation of survival, causal inference, propensity score, and longitudinal models tailored for registry data; produce analyses that meet global regulatory expectations.

Methodological Innovation: Define, program, and implement robust, registry-specific statistical approaches addressing challenges such as missingness, data linkage, confounding, and outcome validation; elevate practice through shared findings.

Cross-Functional and External Collaboration: Provide leadership to clinical, epidemiology, regulatory, and registry operations teams; represent Alexion in external forums, advisory boards, and regulatory discussions.

Standards, Quality, and Compliance: Lead and ensure alignment with AstraZeneca standard methodologies and guidance (e.g., FDA RWE Framework, EMA registry guidance); ensure reproducibility, audit readiness, and transparent reporting in statistical deliverables.

Communication and Influence: Translate analytical results into narratives for executive leadership, briefing documents, and regulatory submissions, creating influence at the program level.

People Leadership and Capability Building: Serve as a mentor and coach to other Real World Data Statisticians within the team; build capability through knowledge-sharing, code review, and career development guidance.

Essential Responsibilities:

Desirable Skills/Experience:

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. Thats why we work, on average, a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

AstraZeneca provides the chance to work at the forefront of rare disease biopharma. Here, complex biology and advanced technology come together to compose transformative medicines for individuals with devastating conditions. At Alexion within AstraZeneca Rare Disease, work is driven by a deep connection to patients lived experiences and a clear purpose that shapes decisions every day. The environment combines the agility of a biotech with the reach and resources of a global organization encouraging curiosity, transparent science, ethical decision-making, and continuous learning. Teams collaborate across disciplines to explore rare opportunities in areas of high unmet need while investing in personal growth through tailored development programs that build both technical mastery and empathy for patients journeys.

Call to Action:

Ready to turn registries into regulatory-grade evidence that advances therapies for people with rare diseases share your CV and start crafting what comes next!

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status.

Date Posted