Executive/Sr Executive - R&D (Process Development)

• Contract Development Manufacturing Organization (CDMO) for peptide- and oligonucleotide-based active pharmaceutical ingredients. By supporting its customers mainly in pharma and biotech, it contributes to the health of millions of patients across the world.
• PolyPeptide serves a fast-growing market, offering products and services from pre clinical to commercial stages. Its broad portfolio reflects the opportunities in drug therapies across areas and with a large exposure to metabolic diseases, including GLP-1.
• Dating back to 1952, PolyPeptide today runs a global network of six GMP-certified facilities in Europe, the U.S. and India. PolyPeptide s shares (SIX: PPGN) are listed on SIX Swiss Exchange.

• We are looking for a highly skilled and motivated professional to join our team as Executive/Sr Executive - Process Development.
• The ideal candidate will possess a strong foundation in Organic Chemistry and proven expertise in peptide chemistry and process development.
• This role requires independent project execution, technical proficiency in DSP, and SPPS synthesis, and a collaborative approach to drive innovation and ensure process excellence.
• The successful candidate will demonstrate exceptional problem-solving abilities, meticulous attention to detail, and a commitment to safety and regulatory compliance.

• - Independently manage projects, including designing Purification Strategies, Reaction Optimization Strategies (ROS) and conducting RD scale experiments
• - Perform Peptide API purification using Chromatography techniques like Preparative HPLC, IEC
• Plan and execute DSP (Down Stream Purification) activities with reproducible

• Having Solid Phase Peptide Synthesis (SPPS) experience
• - Operate, clean, and maintain instruments/equipment in accordance with SOPs
• - Identify and recommend improvements for continuous process optimization
• - Maintain accurate and timely documentation, including online records, process logs, and RD documentation
• - Collaborate effectively across departments to ensure seamless coordination
• - Adhere to all safety protocols and utilize appropriate personal protective equipment (PPE)

• Ph.D. in Chemistry 1-3 yrs relevant experience; M.Sc . in Organic/or equivalent, >5 yrs relevant experience

• - Strong knowledge of peptide chemistry Column Chromatography
• - Hands-on experience with SPPS
• - Ability to work independently and manage multiple projects simultaneously
• - Excellent documentation and organizational skills
• - Strong communication and cross-functional collaboration abilities

• PolyPeptide Group offers an exciting opportunity to work at the forefront of peptide-based
• therapeutics, a rapidly growing and innovative segment of the pharmaceutical industry. As a key member of PolyPeptide team, you will have the opportunity to contribute to a company that is dedicated to the success of its clients and the advancement of peptide science. Join us and be part of a global organization that is shaping the future of life-saving therapies.

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