Executive or Sr. Executive R&D

Roles and Responsibilities

• Develop new APIs through organic synthesis, method development, and optimization.
  
• Conduct literature reviews to stay updated on latest research trends and technologies.
  
• Ensure compliance with GMP guidelines during API manufacturing processes.
  
• Collaborate with cross-functional teams for product development, scale-up, and commercialization.
  
• Perform impurity analysis using techniques like NMR, DSC, etc.
  

Desired Candidate Profile

• MS/M.Sc(Science) degree in Chemistry or Ph.D/Doctorate in Chemical Sciences from a recognized university.
  
• Strong expertise in areas such as API synthesis, organic chemistry, method development/validation/transfer/methodology.
  
• 9-14 years of experience in Research & Development (R&D) or related field.

Key Responsibilities

1. Literature Review & Route Identification
   
• Perform comprehensive literature and patent searches (SciFinder, Reaxys, PubChem, etc.).
  
• Identify and evaluate synthetic routes for APIs, intermediates, and impurities.
  
2. Synthetic Research & Development
   
• Plan and perform multi-step organic synthesis experiments.
  
• Develop and optimize cost-effective and robust synthetic processes.
  
• Work on impurity profiling and synthesis of known/unknown impurities (including nitrosamines/nitroamines).
  
3. Process Optimization & Scale-Up Support
   
• Optimize reaction parameters for higher yield, purity, and reproducibility.
  
• Support process development, kilo-lab trials, and technology transfer.
  
• Address scale-up challenges in collaboration with process R&D teams.
  
4. Analytical Collaboration
   
• Interpret analytical data (HPLC, LC-MS, NMR, IR) for structure confirmation.
  
• Work with Analytical R&D to characterize intermediates, APIs, and impurities.
  
5. Documentation & Compliance
   
• Maintain accurate lab notebooks, experiment records, and reports.
  
• Prepare technical documents for DMFs, ANDAs, and regulatory submissions.
  
• Ensure GLP, GMP, EHS, and data integrity compliance.
  
6. Teamwork & Leadership (For Sr. Executive Level)
   
• Independently lead assigned projects with minimal supervision.
  
• Mentor and guide junior chemists/trainees in lab activities.
  
• Provide technical support for regulatory/customer queries.