Director, Commercial Forecasting

Location:   This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

The Opportunity At Praxis, forecasting is a strategic capability that drives critical business decisions and helps accelerate the delivery of life-changing medicines to patients. The Director of Forecasting will lead all commercial forecasting activities across the portfolio, partnering closely with Finance, Manufacturing, Legal, Commercial, and Executive Leadership to provide clear, data-driven insights that inform strategy, resource allocation, and long-term business planning.  

Primary Responsibilities

Develop, maintain, and continuously improve demand and revenue forecast across the Praxis’ portfolio including pipeline and launch products

Lead cross functional alignment on forecast inputs and assumptions across commercial, finance, manufacturing, and legal teams. 

Develop analyses and sensitivity models to quantify risks and opportunities across a portfolio of near-term launches, supporting go-to-market and investment decisions.  

Integrate various data sources to track early launch performance, identify trends and variances against forecast, and deliver clear actionable insights to senior and executive leadership 

Serve as the primary forecasting resource across the organization, managing multiple concurrent forecast cycles, deliverables, and ad hoc requests in a fast-paced launch environment.

Identify opportunities to improve forecasting accuracy and insight generation through advanced analytics, automation or emerging tools   

Qualifications and Key Success Factors

10+ years of experience in pharmaceutical, biotechnology, healthcare, or life sciences forecasting, commercial analytics, strategic planning, or related disciplines.

Advanced quantitative and analytical expertise, including patient-based forecasting, scenario planning, and market modeling, with a proven track record supporting specialty, rare disease, or other complex therapeutic areas.

Demonstrated success leading forecasting activities for one or more pharmaceutical product launches, including pre-launch planning, launch readiness, and post-launch performance assessment.

Deep understanding of pharmaceutical commercialization, market access, patient flow dynamics, epidemiology, and healthcare data sources.

Proven ability to build trusted partnerships and shape strategic decisions by turning complex data into clear, actionable insights that drive business impact across all levels of the organization.

Thrives in ambiguity, adapting quickly to new information while maintaining focus, momentum, and accountability for delivering results.

Bachelor's degree in Business, Economics, Finance, Statistics, Data Science, Life Sciences, or a related field required; MBA or advanced degree preferred.  

The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement.  You'll need comfort with screen work, basic hand coordination, and focus.  Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.

Compensation & Benefits

At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive.  This includes 99% of the premium paid for medical, dental and vision plans.  We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future?  We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP.  We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns.  Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring.  We aim high, collaborate hard, and produce results.  Let’s achieve the impossible together! 

To round out our world-class total rewards package, we provide annualized base salary compensation in the range listed below.  This range reflects the base salary the Company reasonably expects to pay for the position at the time of posting. Placement within the range will be based on job-related factors, including experience, qualifications, scope of responsibilities, and demonstrated track record of delivering results in similar roles.

Annualized Base Salary $215,000 — $235,000 USD

Company Overview  

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance.  At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders.  Our core Values of Trust , Ownership , Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.

Diversity, Equity & Inclusion Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE ® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.

Attention: Job Scam Alert Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to careers@praxismedicines.com .

Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.