Computational Biologist
Micro Crispr Pvt Ltd · Delhi · onsite · Posted 50d ago
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About this role
Job Title: Computational Structural Biologist
Experience: Fresher to 2 years
Location: Delhi
JD for Computational Structural Biology Team
We are seeking a talented and enthusiastic COMPUTATIONAL STRUCTURAL BIOLOGIST to join our innovative team. As part of our team, you will have the opportunity to work on cutting-edge projects that have a significant impact on patient care and medical research.
Responsibilities:
Computer aided drug discovery for hit identification.
Protein engineering
de novo protein design and computational evaluation
Develop and implement computational models to study protein structures.
Computational antibody engineering
Conduct molecular docking, dynamics simulations, and free-energy calculations.
Experience in handling protein structure prediction tools
Collaborate with experimental scientists to validate computational predictions.
Maintain and optimize computational pipelines for high-throughput analysis.
Data Analysis and Interpretation
Write and present research findings in scientific reports and publications/patents.
Required Skills:
Machine learning based platforms for protein engineering and modelling (AlphaFold, RFDiffusion, RosettaFold)
Generative AI for small molecule and peptide design
Qualification
Master's degree/PhD in Bioinformatics, Computational structural biology
Proficiency in programming languages such as Python or R, or Java.
Strong expertise in structural modeling tools (e.g., Rosetta, PyMOL, Chimera).
Experience in docking (Glide, AutoDock Vina, HADDOCK) and molecular dynamics simulations (AMBER, GROMACS. Desmond) etc
Experience in downstream analysis tools such as MMPBSA, FEP
Immunoinformatic, computational protein engineering tools
Soft Skills:
Ability to work independently and collaboratively in a team-based environment.
Excellent problem-solving skills and the ability to think critically and analytically.
Emphasize interpersonal and problem-solving skills.
Strong communication and teamwork abilities.
Critical thinking and attention to detail.
Ability to manage multiple projects and meet deadlines
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