Analytical R&D(API) - Wet Chemistry & Classical Analytical Techniques

Role & responsibilities

Wet Chemistry Analysis

• Perform qualitative and quantitative analysis using classical wet chemistry techniques.
• Execute manual and automated titrimetric analyses for APIs, intermediates, raw materials, excipients, and finished products.
• Conduct assay, purity, and content determination using validated wet chemistry methods.
• Support analytical characterization and release testing activities.

Analytical Techniques

Hands-on operation, troubleshooting, and interpretation of data generated using:

Titration Techniques

• Manual Acid-Base Titrations
• Redox Titrations
• Complexometric Titrations
• Precipitation Titrations
• Potentiometric Titrations
• Automatic Titration Systems

Moisture & Volatile Determination

• Karl Fischer Volumetric Analysis
• Karl Fischer Coulometric Analysis
• Loss on Drying (LOD)
• Residue on Ignition (ROI)
• Sulphated Ash Determination

Physical Characterization

• Hygroscopicity Studies
• Water Sorption Assessment
• Stability Sample Evaluations
• pH Determination
• Conductivity Measurements
• Density and Specific Gravity Measurements

Method Development & Verification

• Develop, optimize, and verify wet chemistry analytical methods.
• Perform method suitability, accuracy, precision, specificity, linearity, and robustness assessments as applicable.
• Establish analytical procedures for new compounds and development projects.
• Troubleshoot analytical methods and improve method performance.
• Support method transfers and cross-site analytical evaluations.

Investigation Support

• Conduct laboratory investigations related to OOS, OOT, atypical results, and analytical deviations.
• Support root cause identification through scientific experimentation and data evaluation.
• Investigate moisture, stability, and hygroscopicity-related quality concerns.
• Prepare scientifically justified investigation reports and corrective action recommendations.

Instrument Management

• Operate and maintain:
• Auto Titrators
• Karl Fischer Volumetric Systems
• Karl Fischer Coulometric Systems
• FTIR Instruments
• UV-Vis Spectrophotometers
• Moisture Analysers
• Muffle Furnaces
• Analytical Balances
• Coordinate calibration, qualification, preventive maintenance, and troubleshooting activities.
• Ensure compliance and readiness of laboratory equipment.